Hieu Tran
At: 3/10/2017 10:48:47 AM
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Zika may cause miscarriages, thin brain tissue in babies carried to term

Johns Hopkins researchers say that in early pregnancy in mice with complete immune systems, Zika virus can cross the placenta -- intended to protect the developing fetus -- and appears to lead to a high percentage of miscarriages and to babies born with thin brain tissue and inflammation in brain cells.

By administering Zika virus directly into the reproductive tract of pregnant mice that have an intact immune system, the researchers found that the Zika virus appears to create disorganization in the cellular layers of the placenta that keep toxins, bacteria and viruses from crossing. This disorganization could be how the virus penetrates the placenta to infect the fetus. The researchers also discovered a mechanism by which Zika may be keeping antiviral proteins in the body from doing their job of protecting cells from the virus.

These findings, published Feb. 21 in Nature Communications, put scientists one step closer to developing targets for vaccines or other treatments for Zik

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Categories: Featured
Tags: Zika, Johns Hopkins, Health, Placenta, Virus, brain cells

Hieu Tran
At: 5/27/2016 3:20:51 PM
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Zika Preparedness and Response: A Public Health and Legal Perspective by Steve Monroe Phd

With the World Health Organization declaring Zika a public health emergency and with travel associated cases being reported to the CDC, it is critical that health care and public health practitioners, and their legal counsel, consider the role of law and policy in Zika preparedness and response. Speakers will provide an overview of the public health problem posed by Zika, discuss the domestic legal framework for addressing the virus, and highlight ways to coordinate health care and public health legal preparedness.

For the full webinar, check out: https://www.apha.org/~/media/files/pdf/webinars/zika_webinar_slides.ashx

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Categories: Featured
Tags: Steven Monroe, Zika Virus, Public Health, CDC, Webinar

ECN Admin

At: 5/9/2016 12:05:25 AM
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Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3

Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3

View article here:

http://www.cell.com/pb-assets/journals/research/stem/stem1984.pdf

Authors:
Jason Dang, Shashi Kant Tiwari,
Gianluigi Lichinchi, Yue Qin,
Veena S. Patil, Alexey M. Eroshkin,
Tariq M. Rana

 

 

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Categories: Featured
Tags: zika
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